Tuesday, December 18, 2012

Squish the life out of them

Of all the weird cancer treatments I have heard, this one takes the cake. Or crunch. Here it is:

Squish the malignant cells back into normal size and they revert back to normal breast cancer cells.

I am sure squish is the technical term here and you will only 'feel a pinch'.

This study was presented at the American Society for Cell Biology in San Francisco recently so it wasn't done by Dr Jekyll with Igor as an assistant in the dungeon basement of an Eastern European castle.

Before you channel a mammogram machine gone bad, its done at the cell level.

Venugopalan and collaborators grew malignant breast epithelial cells in a gelatin-like substance that had been injected into flexible silicone chambers. The flexible chambers allowed the researchers to apply a compressive force in the first stages of cell development.

Over time, the compressed malignant cells grew into more organized, healthy-looking acini that resembled normal structures, compared with malignant cells that were not compressed. The researchers used time-lapse microscopy over several days to show that early compression also induced coherent rotation in the malignant cells, a characteristic feature of normal development.

Notably, those cells stopped growing once the breast tissue structure was formed, even though the compressive force had been removed.

[Read more at: http://medicalxpress.com/news/2012-12-revert-breast-cancer-cells.html#jCp]

But I am sure you will still only 'feel a pinch'.  

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